We Apply Immunotoxicology Research to Assay Development for Pharmaceutical & Diagnostic Testing
IBT has been a leader in the field of immunotoxicology research and testing for 23 years. We conduct industry-leading research to determine how the immune system reacts to foreign substances such as chemicals, drugs, biopharmaceuticals, environmental contaminants and small-molecule compounds. From this knowledge, we develop novel clinical laboratory tests that scientifically identify and quantify the effects of both chemical and biological substances on immune function.
IBT offers both standard and customized contract testing and assay development services tailored specifically to the individual needs of our pharmaceutical and biotechnology clients.
- Immunotoxicology Services
- Detect and measure the acute and chronic immunotoxic effects of new chemicals, drugs, biopharmaceuticals and environmental contaminants on the immune system
- Evaluate the immunomodulatory effects of small-molecule synthetic drugs, peptides and nucleic-acid-based biotherapeutics such as antisense agents
- Assess immunosuppression, hypersensitivity, immunogenicity/ antigenicity, autoimmunity and immunoefficacy using in vitro and genomic assays of immune function changes during clinical trials
- Immunotoxicology Assays
- In vitro evaluation of immune response
- High-throughput immunotoxicology and inflammatory gene expression profiling
- T-cell, basophil, eosinophil, and phagocytic cell function
- Immune cell phenotyping using blastogenesis, Elispot and flow cytometry
IBT's immunotoxicology services:
IBT offers the following immunotoxicology assays: